Interpol has issued a red notice – its highest arrest alert – for Muammar Gaddafi as the hunt for the former Libyan leader intensifies.

At least 20 people have been killed and several wounded in suicide bombings near a government compound in the Pakistani city of Quetta bordering Afghanistan.

Muammar Gaddafi has probably left the Libyan desert town of Bani Walid and is heading further south with the help of loyalist tribes towards Chad or Niger, Reuters news agency quoted a senior military official in Libya’s new leadership as saying.

Rebels overran Muammar Qaddafi’s compound in Tripoli Tuesday, raising their flag and ripping the head off his statue as they celebrated a symbolic, if not yet real, end to the strongman’s iron-fisted 42-year rule.

Sustained automatic gunfire and a series of explosions rang out in Tripoli overnight as rebels launched efforts to permanantly free the Libyan capital from Muammar Gaddafi’s grasp, according to reports from witnesses and rebels.

Libyan rebels have reportedly taken control of the centre of the oil-rich eastern town of Brega, just 50km east of Tripoli.

Ethnic and criminal violence blamed on gangs has killed 65 people in Pakistan’s financial capital of Karachi, with police the latest victims shot dead in a brazen ambush, officials said Saturday.

A coordinated attack Friday on a British compound in Kabul involving two suicide bombers and a five-hour long firefight between Afghan security troops and attackers who penetrated the complex killed at least 10 people, Afghan officials said.

Libyan opposition forces have pushed further to isolate Tripoli, moving toward a western town that links the capital and Sirte — Libyan leader Muammar Gaddafi’s hometown and a stronghold for his military.

Libyan revolutionary forces have entered the coastal city of Zawiyah, which is located about 50 kilometers (31 miles) west of Tripoli, according to the latest reports.