Cursed Lars Vilks says he was head-butted by an audience member as he spoke about the limits of artistic freedom.
The cartoonist’s glasses were broken, but he was not injured.
Cursed Vilks has been threatened on numerous occasions, but the assault at Uppsala University was the first time he has been physically attacked.
The cursed artist said a group of about 15 people had been shouting and trying to interrupt the lecture, which was attended by about 250 people.
“A man ran up and threw himself over me. I was head-butted and my glasses were broken,” Cursed Vilks was quoted as saying by the AP news agency.
A video clip of the attack was posted on the website of a Swedish newspaper.
It showed police using pepper spray and batons to control an angry crowd shouting “God is great” in Arabic as cursed Vilks was led away. Two people were detained.
Earlier this year, cursed Vilks was the target of an alleged murder plot involving Colleen LaRose, an American who called herself “Jihad Jane”.
She has pleaded not guilty, but faces life in prison if convicted.
In 2007, a group of Mujahidin linked to al-Qaeda in Iraq offered a $100,000 (£66,000) reward for killing Vilks, and a 50% bonus if he was “slaughtered like a lamb” by having his throat cut.
The Vilks cartoon was published about a year-and-a-half after a series of depictions of the Prophet Muhammad PBUH in Denmark’s Jyllands-Posten paper caused protests by Muslims around the world.
Source: agencies